Dr. Zabrina Brumme is a tenured Associate Professor in the Faculty of Health Sciences at Simon Fraser University, and the newly-appointed Laboratory Director at the British Columbia Centre for Excellence in HIV/AIDS (BCCfE). Her laboratory is currently a member of three international HIV cure research consortia (the Canadian HIV Cure enterprise, the USA-based NIH Martin Delaney BELIEVE collaborator, and the European-H2020 HIVACAR consortium) on which her role is to characterize the genetics and dynamics of the latent reservoir and to advise on the design of personalized immunotherapeutic strategies for HIV remission and cure.
Additionally, she is the co-founder of the International HIV adaptation collaborative (IHAC) which has mapped Human Leukocyte Antigen (HLA)-associated escape sites across the HIV genome and demonstrated that immune escape mutations can attenuate HIV replication and protein function.
She has broad expertise in molecular biology, molecular epidemiology, genetics (including drug resistance) and genotype/function relationships in HIV. This expertise translates to her research program, which integrates molecular biology, epidemiology and computational approaches to study HIV genetic diversity and evolution with the goal of informing HIV vaccine and eradication strategies.
Dr. Brumme earned her Bachelor of Science in Microbiology/Immunology and Doctor of Philosophy in Experimental Medicine at the University of British Columbia.