Darrell Tan, MD, PhD, FRCPC

St. Michael’s Hospital
CTN Investigator
Member, Scientific Review Committee
CTN Postdoctoral Fellow: 2007-2008
Dr. Darrell Tan is a clinician scientist at the Li Ka Shing Knowledge Institute at St. Michael’s Hospital in Toronto. He is also an associate professor at the University of Toronto. He is a co-lead for the CTN’s Biomedical Prevention Working Group.

Dr. Tan completed his undergraduate degree at McGill University, majoring in microbiology and immunology and minoring in international development studies. He then obtained his doctorate degree in clinical epidemiology from the University of Toronto.

Dr. Tan’s research focuses on clinical trials in HIV prevention and HIV/STI co-infection. As a co-leader of the CTN’s Working Group and director of the University of Toronto Clinical Research Unit on HIV Prevention, he is leading multiple efforts to optimize the implementation of HIV pre- and post-exposure prophylaxis (PrEP and PEP) in Canada.

He is the principal investigator for CTN 279, Canada’s first PrEP demonstration project, which is examining real-world implementation issues including acceptability, effectiveness, impact on sexually transmitted infection, and strategies for supporting adherence outside the clinical trial setting. He is also leading CTN 287, a trial seeking to optimize adherence to medications and follow-up by incorporating text messaging into patient-doctor communication and by facilitating the administration of PEP by trained nurses under medical directive. He is a contributing author to the CTN-supported national Clinical Practice Guidelines on PEP & PrEP.

Additional research interests of his are the interaction between HIV and common co-infections such as herpes simplex virus type 2 and syphilis and the evaluation of novel antiretroviral PEP regimens.

Dr. Tan became involved with the CTN as a recipient of a Postdoctoral Fellowship Award in 2007 and is now one of the network’s most active investigators. In addition to CTN 287, he is the principal investigator for CTNPT 001, CTNPT 016CTN 240, CTN 254, and a co-investigator for CTN 286.

Click here for a list of studies Dr. Tan has contributed to.

Publications on PubMed