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CTN at CAHR 2018

By April 12, 2018 Uncategorized No Comments

More than 800 researchers, students, community members and policy makers are expected to attend the 27th annual Canadian conference on HIV/AIDS Research (CAHR 2018) in Vancouver from April 26-29. The four-day event features a wide range of sessions including research presentations and workshops to share and discuss advancements in HIV research.

This year’s conference theme is Celebrating our Diversity: Uniting in the Response to HIV with the goal to acknowledge and celebrate diversity among both people with lived experience of HIV, as well as among HIV researchers.

CTN-related special and plenary sessions:

Community Advisory Committee 25th Anniversary event – 25 years of the meaningful involvement of people living with HIV: Community action in research

Wednesday, April 25, 17:15-19:15

This event is supported by CTN and the Canadian Positive People Network. A panel presentation will include current and /or former CAC members, postdoctoral fellows who have participated within the CAC as well as some CTN investigators looking at some of the successes and challenges faced over the years. A reception with light refreshments will follow the presentation.

Cannabis and people living with HIV: New opportunities and challenges ahead

Thursday, April 26, 8:00-14:00

This symposium, cohosted by Chronic Viral Illness Services and the CTN, features a variety of speakers with expertise ranging from basic sciences, epidemiology, clinical medicine, to legal aspects of cannabis. Important regulatory aspects under the new legislation will be described and a community perspective will be provided.

Advancing evidence-based HPV vaccination & screening delivery for people living with HIV and gay, bisexual, and other men who have sex with men

Thursday, April 26, 13:00-15:00

Chaired by Dr. Ann Burchell and co-hosted by Drs. de Pokomandy, Grennan, Salit, Brennan, and Hart. This event provides an opportunity for audience participants to learn about emerging evidence regarding HPV-related vaccination and screening among gbMSM, women, and men living with HIV.

CTN’s postdoctoral fellowship awards program symposium

Friday, April 27, 17:30-19:00

Dr. Kayode Balogun (CTN), University Health Network, Toronto; “A lipidomics approach to identify novel biomarkers for adverse pregnancy outcomes in HIV-positive pregnancy”

Dr. Chelsea Elwood (CTN), University of British Columbia; “Characterization of the vaginal microbiome in pregnant WLWH”

Dr. Nasheed Moqueet (CTN), Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, University of Toronto; “Pre-exposure prophylaxis (PrEP) and the influence of sexual mixing patterns on HIV epidemics among men who have sex with men”

Dr. Jun Chen (China/CTN Special International Fellowship), Shanghai Public Health Clinical Centre, Fudan University, Shanghai, China/McGill University, Montreal; “HIV reservoir size is influenced by inflammatory cytokines but not by microbial translocation”

Dr. Mamadou Kaba (CTN International), University of Cape Town, South Africa; “HIV-exposure, early life feeding practices and delivery mode impacts on faecal bacterial profiles in a South African birth cohort”

Sharing results from 3 Canadian studies involving children & youth living with HIV

Sunday, April 29, 12:30 – 14:00

This knowledge translation event will share the results of three CTN studies: CTN 281 (EPIC4), CTN 236 (HPV in HIV Study), and CTN 291 (CARMA Study).

CTN investigators Drs. Hèléne Côté and Melanie Murray are the conference co-chairs. Other CTN investigators involved in the conference include Clinical Sciences Track co-chairs: Drs. Troy Grennan, Fatima Kakkar, Social Sciences Track co-chairs: Drs. David Brennan, Catherine Worthington and Epidemiology and Public Health Sciences Track co-chair: Dr. Naveed Janjua. The CAHR President is Dr. Curtis Cooper.

Findings from CTN-supported and related studies will be presented during oral abstract and poster sessions; below is a table of these presentations.

Presentation Title

CTN Affiliation

Festa MC, Nitulescu R, Moodie EEM, Wong A, Walmsley S, Vachon ML, Martel-Laferrière V, Hull M, Gill MJ, Cox J, Cooper C, Klein MB; for the Canadian Co-infection Cohort Study. CD4 recovery after the treatment of hepatitis C virus (HCV) in HIV-HCV co-infected adults. Poster presentation.
 
Kronfli N, Nitulescu R, Cox J, Moodie EEM, Cooper C, Wong A, Walmsley S, Klein MB; for the Canadian Co-infection Cohort Investigators. Decreased hepatitis C (HCV) treatment uptake among HIV-HCV co-infected patients with a history of incarceration: A call for action. Poster presentation.

Nitulescu R, Young J, Saeed S, Cooper C, Cox J, Martel-Laferriere V, Hull M, Walmsley S, Tyndall M, Wong A, Klein MB; for the Canadian Co-infection Cohort Investigators. Variation in hepatitis C virus treatment uptake in the era of direct-acting antivirals. Oral presentation.
 
Rossi C, Young J, Saeed S, Wong L, Kronfli N, Klein MB; for the Canadian Co-infection Cohort Investigators. Low rates of failure of direct-acting antiviral therapies for chronic hepatitis C among HIV co-infected Canadians in a real-world clinical setting. Oral presentation.

Saeed S, Moodie EEM, Tyndall M, Hull M, Cooper C, Wong A, Gill J, Walmsley W, Marel-Laferriere V, Cox J, Strumpf EC, Klein MB; for the Canadian Co-Infection Cohort Study. Reductions In healthcare service usage following direct acting antiviral therapy. Poster presentation.





CTN 222
McClymont E, F Coutlée, M Lee, J Raboud, S Walmsley, N Lipsky, D Money; for the CTN 236 HPV in HIV Study Team. Non-Vaccine Oncogenic HPV Persistence Among HPV-Vaccinated Women Living with HIV.CTN 236
Rich AJ, Sereda P, Ye M, Zhu J, Cooper C, Walmsley S, Klein M, Sanche S, Kelly D, Rourke S, Scheim A, Machouf N, Hogg RS; for the Canadian Observational Cohort Collaboration. The HIV clinical care cascade and virologic response over time among transgender people living with HIV in a large multi-site Canadian cohort . Oral presentation.

Chan T, Szadkowski L, Raboud J, Loutfy M, Cooper C, Hogg RS, Sereda P, Ye M, Zhu J, Machouf N, Tsoukas C, Klein MB, Thomas R, Sanche S, WongA, Kroch A, Rourke SB, Kelly D, Walmsley S. Response to initial combined antiretroviral therapy (cART) amongst older people living with HIV in the Canadian Observational Cohort (CANOC). Poster presentation.



CTN 242
Gormley R, Lin SL, Carter A, Webster K, Martin RE, Milloy M-J, Pick N, Howard T, Wang L, Pokomandy A, Loutfy M, Kaida A; for the CHIWOS Research Team. Engagement in HIV care after incarceration experience among women living with HIV in Canada. Oral presentation.

Kaida A, Conway T, Tharao W, Masching R, Pick N, Godoy S, Nicholson V, Beaver K, Gormley R, Kazemi M, Loutfy M, Narasimhan M. The Canadian webinar series on sexual and reproductive health and rights of women living with HIV. Poster presentation.

Kaida A, Nicholson V, Allison Carter, Kath Webster, Rebecca Gormley, Paul Sereda, Robert S. Hogg, Alexandra de Pokomandy, Mona Loutfy; for the CHIWOS Research Team. Mortality among women living with HIV enrolled in Canada's largest community-based cohort study. Oral presentation.

Carter A, Greene S, Money D, Sanchez M, Webster K, Nicholson V, Brotto LA, Hankins C, Kestler M, Pick N, Salters k, Proulx-Boucher K, O’Brien N, Patterson S, Wang L, Tiamiyu L, Pokomandy A, Loutfy M, Kaida A; for the CHIWOS Research Team. Is awareness of the HIV prevention benefits of ART associated with lower anxiety during sex? A cross-sectional analysis of women living with HIV in Canada. Poster presentation.

Carter A, Greene S, Money D, Sanchez M, Webster K, Nicholson V, Brotto LA, Hankins C, Kestler M, Pick N, Salters K, Proulx-Boucher K, O’Brien N, Patterson S, Pokomandy A, Loutfy M, Kaida A; for the CHIWOS Research Team. The importance of sex for women living with HIV in Canada. Poster presentation.

Mitchell-Foster S, Jaworsky D, Tom C, West V, Paul A, Jaleel M, Webster K, Gormley R, Carter A, Loutfy M, Pokomandy A, Kaida A; for the CHIWOS Research Team. Geographic differences in experiences of HIV care among women living with HIV in Northern British Columbia compared with the rest of the province. Poster presentation.

Puskas CM, Pick N, Carter A, Wang L, Loutfy M, Pokomandy A, Webster K, Gormley R, Kaida A; for the CHIWOS Research Team. Looking at the levels: examining the nuances of tiered antiretroviral therapy (ART) adherence among women with HIV in Canada. Poster presentation.

Underhill A, Wu W, Logie C, Jaworsky D, Tharao W, Lacombe-Duncan A, Muchenje M, O’Brien N, Islam S, Webster K, Otis J, Gormley R, Narasimhan M, Arkell C, de Pokomandy A, Kaida A, Loutfy M; for the CHIWOS Research Team. Prevalence and correlates of HIV disclosure worries among women living with HIV in Canada. Oral presentation.

Hawa R, Kazemi M, Warren W, Islam S, Ndung’u M, Logie C, Underhill A, Jaworsky D, Tharao W, Conway T, Persad P, Webster K, de Pokomandy A, Kaida A, Loutfy M; for the CHIWOS Research Team. High resilience of women living with HIV with psychosocial enabling factors: implications for practice. Oral presentation.

Authors to be confirmed. Mâmawi wâhkôtowin: An arts-based approach to understanding wellness and living with HIV among Indigenous women in Winnipeg, Canada (CHIWOS). Oral presentation.

Shokoohi M, Bauer GR, Lacombe-Duncan A, Kaida A, de Pokomandy A, Gagnier B, Kazemi M, Loutfy M; for the CHIWOS Research Team. Social determinants of health and self-rated health status: A comparison between women living with HIV and women from the general population in Canada.

Lacombe-Duncan A, Persad Y, Tarshis S. HIV-related healthcare access for trans women living with HIV: A systematic review. Oral presentation.




















CTN 262
Hart, TA, Noor, SW, Vernon, JRG, Antony, M, O’Cleirigh, C. The Sexual Confidence Study: Cognitive behavioural therapy for social anxiety and HIV prevention for gay and bisexual men. Oral presentation.CTN 265
Durand M, Sinyavskaya L, Chartrand-Lefebvre C, Baril JG, Trottier S, Trottier B, Harris M, Walmsley S, Conway B, Wong A, Routy JR, Kovacs C, MacPherson PA, Monteith KM, Mansour S, Zhu Z, Tremblay CL. HIV as risk factor for Polypharmacy: data from the Canadian HIV and Aging Cohort .

Sadouni M, Durand M, Boldeanu I, Tremblay CL, Chartrand-Lefebvre C. Differential expression of protective CD73+ memory CD4 T-cells and Regulatory T-cells (Tregs) in virally supressed HIV+ adults with diagnosed atherosclerosis.

Mohammad Ali Jenabian. Epicardial fat is increased in the HIV population and associated to coronary plaque burden.





CTN 272
Russell E, Campbell AR, Nesbitt A, Côté HCF, Pick N, Hsieh A, Maan EJ, Murray MCM and the CIHR team on Cellular Aging and HIV Comorbidities in Women and Children (CARMA). Metabolic and Cardiovascular Health Among Women Living with HIV Enrolled in the CARMA cohort. Poster presentation.

Campbell AR, Borhani M, Gordon S, Nesbitt A, Côté HCF, Maan EJ, Pick N, Murray MCM and the CIHR team on Cellular Aging and HIV Comorbidities in Women and Children (CARMA). Comorbidity and Polypharmacy Among Women Living with HIV in British Columbia. Poster presentation.
CTN 277
Bitnun A, Kakkar F, Brophy J, Samson LE, Hawkes MT, Read SE, Lee T, Ransy DG, Chomont N, Pagliuzza A, Sandstrom P, Kim J, Lavigne C, Lavoie SS, Wender PA, Soudeyns H, EPIC4 Study Group. HIV reservoir size in peripheral blood of perinatally infected children: results from EPIC4 (Early Pediatric Initiation, Canada Child Cure Cohort) Study. Oral presentation.

Dieumegard HK, Ransy DG, Salem Fourati I, Taillefer SS, Janelle-Montcalm A, Caty M, Valois S, Read S, Lapointe N, Boucher M, Samson L, Hawkes MT, Lamarre V, Kakkar F, Bitnun A, Brophy J, Soudeyns H, EPIC4 Study Group. Sustained virologic suppression differentially influences HIV-specific cell-mediated immune responses in perinatally infected children and adolescents. Poster presentation.

Hawkes M, Mocanu V, Soo J, Brophy J, Kakkar F, Bitnun A, Samson L, Read S, Dieumegard H, Janelle-Montcalm A, Ransy D, Soudeyns H, EPIC4 Study Group. Microbial translocation, inflammation and endothelial activation in vertically HIV-1 infected children. Oral presentation.

Kakkar F, Sauve L, Lee T, Samson L, Brophy J, Hawkes MT, Alimenti A, Vaudry W, Soudeyns H, Singer J, Bitnun A, EPIC4 Study Group & Canadian Perinatal HIV Surveillance Program (CPHSP). 90/90/90? How are Canadian infants and children measuring up to UNAIDS targets for 2020? Oral presentation.

Kakkar F, Lee T, Samson L, Brophy J, Hawkes MT, Ransy DG, Soudeyns H, Bitnun A, EPIC4 Study Group. Predictors of viral suppression among children in Canada initiating antiretroviral therapy in the EPIC4 cohort: Role of socio-economic factors. Oral presentation.






CTN 281
Côté, J., Cossette, S., Ramirez Garcia, P., Worthington, C., dePokomandy, A., Miranda, J., Auger, P., Rouleau, G., Leblanc, J. Smoking rates, physical activity level, diet quality and perception regarding health behavior change. CTN 288
Ordono MS , Money DM, Gadawski I, Sattha B, Côté HC, Boucoiran I, and CIHR Team in Cellular Aging and HIV Comorbidities in Women and Children (CARMA)
. Preeclampsia is Associated with High Placenta mtDNA Content Among Women Living with and without HIV. CTN 291
Early Acceptability and Cytologic Outcomes of Anal Cancer Screening in Men Who Have Sex with Men (MSM) Living With HIV: The HPV-SAVE Study CTN 292
Lee H, Colyer S, Armstrong HL, Cox J, Lambert G, Hart TA, Kroch A, Wong J, Bitera R, Wilton J, Lachowsky N, Grace D, Jollimore J, Hogg R, Moore D. Trends in HIV diagnoses by age and ethnicity among men who have sex with men (MSM) in British Columbia, Ontario, and Quebec: 2006-2015. Oral Presentation.

Doyle CM, Maheu-Giroux M, Lambert G, Messier-Peet M, Apelian H, Grace D, Hart TA, Moore DM, Lachowsky NJ, Jollimore J, Olarewaju G, Tooley L, Rodrigues R, Cox J.
Combination HIV prevention among Montreal gay, bisexual, and other men who have sex with men in the PrEP era: a Latent Class Analysis. Oral Presentation.

Apelian H, Messier-Peet M, Cox J, Hart TA, Grace D, Moore DM, Lachowsky NJ, Jollimore J, Armstrong H, Olarewaju G, Tooley L, Rodrigues R, Adam B, Alary M, Blais M, Coté P, Flores-Aranda J, George C, Lebouché B, Monteith K, Otis J, Serhir B, Tan D, Thomas R, Tremblay C, Lambert G. PrEP-use experience among gay, bisexual, and other men who have sex with men (gbMSM) in Montreal. Oral Presentation.

Gaspar M, Marshall Z, Adam B, Grace D. A Tale of Two Epidemics: Gay and Bisexual Men’s Mental Health Service Needs and Experiences in a Period of Effective Biomedical HIV Prevention and Treatment Options. Oral Presentation.

Grewal R, Yeung A, Brisson M, Grennan T, De Pokomandy A, Cox J, Lambert G, Moore D, Coutlee F, Deeks S, Franco EL, Gardner S, Griffiths D, Isaranuwatchai W, Jollimore J, Murray J, Ogilvie G, Sauvageau C, Tan D, Tooley L, Adam B, Armstrong H, Gaspar M, George C, Grace D, Hart T, Burchell A. Human papillomavirus (HPV) vaccine uptake in gay, bisexual, and other men who have sex with men (gbMSM) in Montreal, Toronto, and Vancouver. Poster presentation.

Hart TA, Noor SW, Cox J, Moore DM, Lachowsky NJ, Jollimore J, Armstrong HL, Tooley L, Rodrigues R, Messier-Peet M, Olarewaju G, Grace D. Knowledge Attitudes regarding Treatment as Prevention (TasP) in a Canadian Multi-Site Study Among Men who have Sex with Men. Poster presentation.

Messier-Peet M, Apelian H, Lambert G, Hart T, Grace D, Moore DM, Lachowsky NJ, Jollimore J, Olarewaju G, Armstrong H, Tooley L, Rodrigues R, Adam B, Alary M, Blais M, Coté P, Flores-Aranda J, George C, Lebouché B, Monteith K, Otis J, Serhir B, Tan D, Thomas R, Tremblay C, Cox J. Applying a conceptual model of access to explore access to PrEP in a population-based sample of gay, bisexual, and other men who have sex with men (gbMSM) Poster presentation.

Moqueet N, Noor SW, Hart TA, Armstrong HL, Lachowsky NJ, Burchell A, Lambert G, Cox J, Moore DM, Simkin A, Vargas ER, Tan D, Mishra S. Quantifying sexual mixing patterns among gay, bisexual, and other men who have sex with men in Canada: implications for modeling HIV/STI transmission. Poster presentation.

Armstrong HL, Lachowsky NJ, Wang L, Bacani N, Olarewaju G, Tooley L, Rodrigues R, Messier-Peet M, Noor S, Mishra S, Scheim A, Hull M, Jollimore J, Lambert G, Cox J, Grace D, Hart TA, Moore DM. HIV and HIV risk behaviour among gay, bisexual, and other men who have sex with men in Vancouver, Toronto, and Montreal: Preliminary comparisons from the Engage Study Poster Presentation.

















CTN 300
Frailty Phenotype in Canadian Men and Women with HIV Poster Presentation.

Cognition, from Biology to Daily Function and Quality of Life (M-J Brouillette). Oral Presentation.
CTNPT 005
Accuracy and Acceptability of Self- Versus Clinician-Collected Anal Swabs for Cytology in HIV-Positive Men: Preliminary Results from the NOMAD-2 Study. CTNPT 023

Be sure to keep a look out for CTN investigators as they present their work from non-CTN studies! 

Research for treatments, prevention and a cure